Educating Clinicians & Improving Patient Care
Delivering evidence-based education to improve diagnosis, treatment, and outcomes for children with PANS/PANDAS.

• Hosted an expert led research webinar that examines the roles of neuroimmune and epigenetic factors in children with PANS/PANDAS, and discusses whether these conditions are best understood as autoimmune, autoinflammatory, or both. This in-depth learning opportunity provided Drs. Dritan Agalliu (Columbia University), Madeleine Cunningham (University of Oklahoma), Russell Dale (University of Sydney, AU), and Jennifer Frankovich (Stanford University) the opportunity to present their research findings related to PANS and PANDAS and answer questions. LEARN MORE
• Delivered a CME-accredited webinar for psychiatrists to improve recognition and management of PANS/PANDAS. In Early Recognition & Treatment of Neuroimmune Psychiatric Conditions: A Paradigm Shift in Neuropsychiatry, Juliette C. Madan, MD, MS (Dartmouth) places emphasis on distinguishing primary psychiatric illnesses from immune-mediated presentations and on tailoring psychiatric and medical interventions to meet the needs of these complex cases. LEARN MORE
• Participated in key national conferences to share knowledge and foster collaboration with leading professional organizations, including the International OCD Foundation (IOCDF), the American Academy of Pediatrics (AAP), and the American Nurses Association (ANA).
• Published educational advertisements in professional outlets to reach frontline clinicians from a variety of medical specialties.

Strengthening Clinical Resources & Diagnostic Clarity
Offering clinical resources that support early identification, differential diagnosis, and appropriate care.

• Updated Seeing Your First Child with PANS/PANDAS to guide clinicians through initial evaluation and care. This valuable resource underwent a review and update by Allison Vreeland, PhD (Stanford University). READ NOW
• Updated Comparing PANS/PANDAS and Traditional Childhood OCD clarify differential diagnosis and support appropriate treatment pathways. READ NOW

Leadership in Standards of Care
Calling for up-to-date, evidence-based clinical guidance in pediatric neuropsychiatric care.

In 2025, we issued an urgent appeal to the American Academy of Pediatrics (AAP) urging revision of its PANS Clinical Report to ensure pediatricians have access to the most current, evidence-based research and actionable diagnostic and treatment guidance. Our appeal highlighted that the AAP’s report omitted more than 50 relevant peer-reviewed studies published between 2018–2025, which negatively influenced conclusions and guidance for clinicians. We called for immediate updates to include this full body of science, to advise appropriate testing (including strep testing when indicated), and to commit to regular, evidence-based guideline updates in collaboration with expert clinical networks. LEARN MORE

Advancing Research & Scientific Discovery
Advancing research on infection-triggered neuropsychiatric disorders and immune-related brain conditions.

• Launched concise, clinician-focused research summaries translating emerging evidence into practice
• Published a comprehensive Research (2018–2025) webpage to centralize and elevate the evidence base LEARN MORE
• Supported investigator-led science through targeted grants to the Agalliu Lab at Columbia University and the Stanford Immune Behavioral Health clinic