PPN Facebook PPN Twitter PPN Instagram


The Role of Adaptive Immunity and Genetic Risk Factors in Vascular and Neuronal Dysfunction in Post-Infectious Autoimmune Encephalitis

Presented by Dritan Agalliu, Ph.D.
Associate Professor, Departments of Neurology, Pathology and Cell Biology, Columbia University Irving Medical Center


Target Audience:
Physicians, nurse practitioners, physician assistants, nurses, and therapists.

Learning Objectives
Participants will be able to:

  1. Evaluate the causes of Autoimmune Encephalitis, Post-Infectious Autoimmune Encephalitis and the immune mechanisms that induce the disease.
  2. Determine how Th17 lymphocytes induce blood-brain barrier damage, neuroinflammation and cause neuronal impairment in animal models for post-infectious basal ganglia encephalitis.
  3. Review the cytokines that are present in sera from PANDAS/PANS patients and their effect on the blood-brain barrier in vitro.
  4. Consider the genetic risk factors identified in PANDAS/PANS that predispose the children to develop the disease and incorporate a team-based approach to counsel and guide patients and families diagnosed with PANDAS/PANS.

Estimated Time for Completion: 60 minutes

Projects In Knowledge® is accredited by the Accreditation Council for Continuing Medical Education(ACCME) to provide continuing medical education for physicians. Projects In Knowledge® designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Projects In Knowledge®(PIK)is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center’s Commission on Accreditation. Upon completion of this course, participants will be awarded 1.0 nursing contact hour(s).

DISCLAIMER: Accreditation refers to educational content only and does not imply ANCC, or PIK endorsement of any commercial product or service.


Questions? Contact us at cme@pandasppn.org.