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CME-ACCREDITED EDUCATION

The Role of Adaptive Immunity and Genetic Risk Factors in Vascular and Neuronal Dysfunction in Post-Infectious Autoimmune Encephalitis

Presented by Dritan Agalliu, Ph.D.
Associate Professor, Departments of Neurology, Pathology and Cell Biology, Columbia University Irving Medical Center

PANS/PANDAS Brain

Target Audience:
Physicians, nurse practitioners, physician assistants, nurses, and therapists.

Goal:
The goal of this activity is to provide an overview of Autoimmune Encephalitis, Post-Infectious Autoimmune Encephalitis and Immune Mechanisms that may drive the disease.

Learning Objectives
Participants will be able to:

  1. Evaluate the causes of Autoimmune Encephalitis, Post-Infectious Autoimmune Encephalitis and the immune mechanisms that induce the disease.
  2. Determine how Th17 lymphocytes induce blood-brain barrier damage, neuroinflammation and cause neuronal impairment in animal models for post-infectious basal ganglia encephalitis.
  3. Review the cytokines that are present in sera from PANDAS/PANS patients and their effect on the blood-brain barrier in vitro.
  4. Consider the genetic risk factors identified in PANDAS/PANS that predispose the children to develop the disease and incorporate a team-based approach to counsel and guide patients and families diagnosed with PANDAS/PANS.

Estimated Time for Completion: 60 minutes

Dates:
Release Date: May 01, 2021
Termination Date: April 30, 2022

Credit Available
Physicians: 1.00
Physician Assistants: 1.00
Nurses: 1.00
JOINT ACCREDITATION STATEMENT

DISCLAIMER: Accreditation refers to educational content only and does not imply ANCC, or PIK endorsement of any commercial product or service.

DISCLOSURE INFORMATION: Projects In Knowledge® adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CE activity, including faculty, planners, reviewers or others are required to disclose all relevant financial relationships with ineligible entities (commercial interests)*. All relevant conflicts of interest have been mitigated prior to the commencement of the activity.

Dritan Agalliu, Ph.D., has no relevant financial relationships to disclose.

START ACTIVITY

Questions? Contact us at cme@pandasppn.org.

JOINT ACCREDITATION STATEMENT


In support of improving patient care, this activity has been planned and implemented by PANDAS Physicians Network and Projects In Knowledge®.. Projects In Knowledge is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Physicians
Projects In Knowledge® designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Physician Assistants
Projects In Knowledge® has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.0 AAPA Category 1 Credit(s)™. Approval is valid until 04/30/2022. PAs should only claim credit commensurate with the extent of their participation.

Nurses
Upon completion of this course, participants will be awarded 1.0 nursing contact hour(s). Joint Accreditation Nursing Provider Number: 4008235

DISCLAIMER:
Accreditation refers to educational content only and does not imply ANCC, or PIK endorsement of any commercial product or service.

DISCLOSURE INFORMATION: Projects In Knowledge® adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CE activity, including faculty, planners, reviewers or others are required to disclose all relevant financial relationships with ineligible entities (commercial interests)*. All relevant conflicts of interest have been mitigated prior to the commencement of the activity.

Dritan Agalliu, Ph.D., has no relevant financial relationships to disclose.