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PANS, PANDAS, AE webinar now available on demand.

The Role of Adaptive Immunity and Genetic Risk Factors in Vascular and Neuronal Dysfunction in Post-Infectious Autoimmune Encephalitis

Presented by Dritan Agalliu, Ph.D.
Associate Professor, Departments of Neurology, Pathology and Cell Biology, Columbia University Irving Medical Center

PANS/PANDAS Brain

CLINICIAN RESOURCES FOR PANS/PANDAS

DIAGNOSTIC GUIDELINES

PPN maintains the most up to date clinical guidelines for diagnosing PANS/PANDAS. Guidelines will always be based on published information and further refined and explained by the Diagnostics & Therapeutics Committee.

TREATMENT OPTIONS

PPN Treatment Options aim to provide the breadth of potential therapies for PANS/PANDAS, updated for the latest research and experience of clinicians. Treatment options include antibiotics, steroids, IVIG, and behavioral therapy.

SEEING YOUR FIRST PATIENT

“Seeing Your First Child with PANDAS/PANS” is a medical guide consisting of: overview and current theories, symptoms and diagnostic criteria, workup recommendations, and expectations.

FLOWCHARTS

The flowcharts for diagnosing and treating PANS/PANDAS include a process for determining the appropriate diagnosis and symptom severity-based treatment protocols for mild, moderate, and severe/extreme cases.

OUR MISSION

The PPN mission is to maintain the industry standard PPN Guidelines for Diagnostics and Therapeutics, foster continuous education and communication within the multi-disciplinary medical community and to sponsor research for developing diagnostic tests, treatment protocols and a cure for PANDAS/PANS within this generation.

Journal of Child and Adolescent Psychopharmacology

Evaluation of Intravenous Immunoglobulin in PANS

“In this population of PANS subjects, all psychometric endpoints studied exhibited statistically significant decreases following six infusions of IVIG…The durability of response is also noteworthy.”

Journal of Neuropsychiatry

Cognitive, Graphomotor, and Psychosocial Challenges in PANDAS

“These findings indicated relative difficulties with aspects of executive and motor functions. Although evaluations were performed following the resolution of acute symptoms, ongoing and significant academic difficulties and emotional, behavioral, and social concerns were targets for clinical intervention and support.”

Frontiers in Psychiatry

Autoantibody Biomarkers for Basal Ganglia Encephalitis in Sydenham Chorea and PANDAS

“Our results suggest that the panel of four antineuronal antibodies and CaMKII activation assays successfully identify acute illness in PANDAS, providing opportunities for rapid and accurate diagnosis and treatment.”

BECOME A MEMBER

► Receive email alerts on new research, guidelines, and treatment protocols
► Option to be recognized as a practitioner who works with PANS/PANDAS patients
► Receive occasional members only benefits

STUDIES CURRENTLY RECRUITING

Access a list of PANS, PANDAS, and Basal Ganglia Autoimmune Encephalitis studies currently seeking participants.

CHANGE THE COURSE OF MENTAL ILLNESS WITHIN A GENERATION

PPN’s goal is to help medical professionals understand, diagnose and treat PANS (Pediatric Acute-onset Neuropsychiatric Syndrome) and PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections) by providing to them quality research, diagnostic and treatment tools. Your donation dollars will not only help maintain PPN’s tools, but will help further prove that the immune system can cause such psychological distress.

PANS/PANDAS resources for clinicians.