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Dritan Agalliu, PhD
Columbia University – Associate Professor of Pathology and Cell Biology (in Neurology)

Dritan Agalliu

Announcement:
PPN Awards Funding to the Agalliu Lab for Immune Mediated OCD, PANDAS/PANS Research

PPN awards the Agalliu Lab funding to support Dr. Uğur Akcan’s study which will provide insight into the mechanisms by which the RXRA genetic risk factor identified in PANDAS children affects immune responses that trigger neuropsychological changes, including obsessive-compulsive behaviors.

PUBLISHED RESEARCH (PANS/PANDAS)

Distinct Th17 effector cytokines differentially promote microglial and blood-brain barrier inflammatory responses during post-infectious encephalitis
https://doi.org/10.1101/2023.03.10.532135

Th17 lymphocytes drive vascular and neuronal deficits in a mouse model of postinfectious autoimmune encephalitis
10.1073/pnas.1911097117

Hello from the Other Side: How Autoantibodies Circumvent the Blood-Brain Barrier in Autoimmune Encephalitis
doi:10.3389/fimmu.2017.00442

CNS autoimmune disease after Streptococcus pyogenes infections: animal models, cellular mechanisms and genetic factors
doi:10.2217/fnl.16.4

Group A Streptococcus intranasal infection promotes CNS infiltration by streptococcal-specific Th17 cells
 doi:10.1172/JCI80792.

INTERVIEWS AND VIDEOS

Short summary video illustrating the findings of the Agalliu lab.