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Dritan Agalliu, PhD
Columbia University – Associate Professor of Pathology and Cell Biology (in Neurology)

FEATURED WEBINAR:
How Peripheral Infection Triggers Brain Inflammation

The 90 minute on-demand webinar includes a presentation followed by a Q and A.

Dritan Agalliu webinar

PUBLISHED RESEARCH (PANS/PANDAS)

Distinct Th17 effector cytokines differentially promote microglial and blood-brain barrier inflammatory responses during post-infectious encephalitis
Charlotte R. Wayne, Luca Bremner, Travis E. Faust, Violeta Durán-Laforet, Nicole Ampatey, Sarah J. Ho, Philip A. Feinberg, Panos Arvanitis, Bogoljub Ciric, Shannon L. Delaney, Wendy Vargas-Deming, Susan Swedo, Vilas Menon, Dorothy P. Schafer, Tyler Cutforth, Dritan Agalliu
bioRxiv 2023.03.10.532135; doi: https://doi.org/10.1101/2023.03.10.532135

Th17 lymphocytes drive vascular and neuronal deficits in a mouse model of postinfectious autoimmune encephalitis
Maryann P. Platt, Kevin A. Bolding, Charlotte R. Wayne, Sarah Chaudhry, Tyler Cutforth, Kevin M. Franks, Dritan Agalliu
Proceedings of the National Academy of Sciences Mar 2020, 117 (12) 6708-6716; DOI: 10.1073/pnas.1911097117

Hello from the Other Side: How Autoantibodies Circumvent the Blood-Brain Barrier in Autoimmune Encephalitis
Platt MP, Agalliu D, Cutforth T. Hello from the Other Side: How Autoantibodies Circumvent the Blood-Brain Barrier in Autoimmune Encephalitis. Front Immunol. 2017;8:442. Published 2017 Apr 21. doi:10.3389/fimmu.2017.00442

CNS autoimmune disease after Streptococcus pyogenes infections: animal models, cellular mechanisms and genetic factors
Cutforth T, DeMille MM, Agalliu I, Agalliu D. CNS autoimmune disease after Streptococcus pyogenes infections: animal models, cellular mechanisms and genetic factors. Future Neurol. 2016;11(1):63-76. doi:10.2217/fnl.16.4

Group A Streptococcus intranasal infection promotes CNS infiltration by streptococcal-specific Th17 cells
Thamotharampillai Dileepan1, Erica D. Smith2, Daniel Knowland2, Martin Hsu2, Maryann Platt3, Peter Bittner-Eddy1, Brenda Cohen1, Peter Southern1, Elizabeth Latimer4, Earl Harley5, Dritan Agalliu2,3, and P. Patrick Cleary1
Published December 14, 2015. J Clin Invest. 2015. doi:10.1172/JCI80792.

FEATURED WEBINAR
Click arrow to begin.

Looking at the Brains of PANDAS/PANS Children: How Peripheral Infection Triggers Brain Inflammation discusses:

✓ Molecular atlas of transciptome changes impacting the Blood Brain Barrier (BBB)

✓ Cytokine profiles of children sick with acute onset PANDAS/PANS

✓ IL17A and GM-CSF impact the BBB and microglia of the brain

INTERVIEWS AND VIDEOS

Short summary video illustrating the findings of the Agalliu lab.