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Strep PANDAS PANS TH17

Group A Streptococcus intranasal infection promotes CNS infiltration by streptococcal-specific Th17 cells
Thamotharampillai Dileepan1, Erica D. Smith2, Daniel Knowland2, Martin Hsu2, Maryann Platt3, Peter Bittner-Eddy1, Brenda Cohen1, Peter Southern1, Elizabeth Latimer4, Earl Harley5, Dritan Agalliu2,3, and P. Patrick Cleary1
Published December 14, 2015. J Clin Invest. 2015. doi:10.1172/JCI80792.

Th17 lymphocytes drive vascular and neuronal deficits in a mouse model of postinfectious autoimmune encephalitis
Maryann P. Platt, Kevin A. Bolding, Charlotte R. Wayne, Sarah Chaudhry, Tyler Cutforth, Kevin M. Franks, Dritan Agalliu
Proceedings of the National Academy of Sciences Mar 2020, 117 (12) 6708-6716; DOI: 10.1073/pnas.1911097117

Author’s Take Video: Linking intranasal group A Streptococcus infection to CNS complications
Drs. Pat Cleary and Dritan Agalliu
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Video: “Group A Streptococcus intranasal infection promotes CNS infiltration by streptococcal-specific Th17 cells”.
Drs. Pat Cleary and Dritan Agalliu
Click the white arrow to begin the video.